Webinars

Spatial biology without compromises: tissue morphology preservation and efficient antibody elution

Resource: Spatial biology without compromises: tissue morphology preservation and efficient antibody elution

Abstract: Spatial immunofluorescence is a game-changer technique in the field of immune-oncology, neuroscience and infectious diseases. When developing multiplex immunofluorescence panels tissue preservation and efficient antibody removal are key factors to ensure signal specificity. COMET™ is based on a microfluidic technology and performs sequential immunofluorescence (seqIF™), with repetitive cycles of staining, imaging and elution. COMET™ performs fast and finely controlled antibody staining incubations without harsh tissue photobleaching or tissue ablation. In this webinar, we will highlight how to verify tissue integrity and demonstrate how COMET™ guarantees efficient  antibody elution while ensuring morphology preservation. We will also show how to assess epitope stability during seqIF™ assay and how COMET™ enables marker stability up to 20 cycles across different tissue types and species.

Speaker: Dr. Pino Bordignon, Team Leader Application Research