In situ hyperplex techniques to study the cytotoxicity of immunotherapies in non-small cell lung cancer

In this webinar, Dr. Amine Majdi, postdoctoral fellow at the Centre de Recherche des Cordeliers, will share his research focusing on the emerging role of immunogenic cell deaths in non-small cell lung cancer (NSCLC) and its correlation with prognosis based on spatial cell distribution.

Tissue architecture not only establishes the groundwork but also influences cell interactions and phenotypes significantly. Dr. Majdi will discuss his recent investigations utilizing the COMET™ platform that his team uses to analyze and map tissues effectively. Simultaneous visualization of multiple biomarkers is essential, facilitated by multiplex immunofluorescence (mIF). This technique yields comprehensive insights into cell phenotypes while preserving spatial context and neighboring information.

Key learning objectives

• Learn about the latest research regarding NSCLC and immunotherapy-associated cytotoxicity with the COMET™ platform
• Discover how to obtain highly reproducible, hyperplex data with a fully automated workflow on COMET
• Explore how to use spatial biology to identify and validate biomarkers

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