Marker Database

Embrace spatial biology effortlessly using your off-the-shelf antibodies with the flexibility provided by COMET™ and its SPYRE™ Antibody Panels

Begin your spatial biology journey with Lunaphore’s marker protocols and SPYRE™ Antibody Panels. At Lunaphore, we prioritize quality and transparency. To ensure this, we have tested antibodies in-house from external suppliers and categorized them into the following groups, as shown in Figure 1.

For qualified markers, a working clone is identified, the protocol is optimized for the associated tissue type that is available and tested towards repeatability and antibody specificity and sensitivity are assessed on a control tissue.

For verified markers, protocols are tested towards reproducibility as well as intra- and inter-tissue robustness.

Lunaphore has developed SPYRE™ Antibodies and SPYRE™ Antibody Panels, whose protocols are tested towards reproducibility and robustness. In addition, the immunofluorescent staining is cross-validated against IHC as the gold standard, and antibodies are lot-to-lot tested. SPYRE™ Antibodies are supplied and supported by Lunaphore.

Published markers are collected from external scientific publications using COMET™, including peer-reviewed and preprint articles. Their validation level is not granted by Lunaphore, please contact the author of the study for more information.

How to integrate a new marker?

To enable a quick integration process with minimal user investment, customers receive exclusive access to the Panel Builder and entire marker protocol library, including antibody information. 

The library of COMET™ markers keeps growing, and more published markers are reported to have been tested on COMET™ across different research projects: