COMET™

COMET™'s product front view

Rapid hyperplex made easy.

Your hyperplexing platform for spatial biology made easy

A full-stack solution capable of visualizing up to 40 markers in a single sample within a day.

An open solution without secrets

You are the owner of your research. Use your off-the-shelf, label-free antibodies and customize your protocols.

A high-throughput, high-insight platform

Get fast and deep insight into your samples’ spatial make-up with 4 slide capacity.

Using COMET™ means that we don’t need to conjugate or do anything to our primary antibodies, and for us this is important as we have a lot of in-house generated antibodies that we would like to apply.

Dr. Charlotte Stadler's profile portrait

Dr. Charlotte Stadler

Head of the National Spatial Proteomics Facility and Co-Director at the Spatial and Single Cell Biology Platform at SciLifeLab

DAPI Ki67 CD8 CD3 CD68 PARP A multiplexed image of colorectal core sample (human FFPE).

DAPI Ki67 CD8 CD3 CD68 PARP A multiplexed image of colorectal core sample (human FFPE).

Lunaphore’s COMET™ is intuitive and flexible, we were able to work up a 30-plex IHC panel using our existing primary antibodies over a number of weeks. The data we generated provided us with a spatial, high-dimensional overview of immune infiltrate in COVID-19 placentitis and insight into the processes driving the pathology.

Dr. Matthew Pugh's profile portrait

Dr. Matthew Pugh

Institute of Immunology and Immunotherapy, University of Birmingham

24-plex of human placenta in Sars-Cov-2 infected patient for COMET™

24-plex of human placenta in Sars-Cov-2 infected patient for COMET™

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24 markers on tonsil tissue.

Total protocol time: 5h. Fully automated on COMET™.

COMET™ helps by:

Allowing you to exploit the full capabilities of spatial biology in your research
  • Gain a deep understanding of your tissue context and architecture.
  • Leverage spatial knowledge to unveil potential new biomarkers.
  • Gain true insight into immune microenvironments.
Leveraging the full potential of your discoveries
  • Go from a discovery approach to zooming into your markers of interest all in one device.
  • Integrate your RNA data with your proteomics data to gain true insight in biological processes.
Eliminating the complexity of spatial biology
  • Move to a “sample in insight out” approach with minimal user investment.
  • Get access to top-notch experts to support you in your research.

Join the COMET™
Revolution.

Fully automated workflow

COMET™ integrates the staining and imaging steps to avoid instrument manipulation during the entire process.

Use of your preferred antibodies

COMET™ is designed to satisfy researchers’ flexibility needs and works with off-the-shelf, label-free antibodies. As simple as that.

Hyperplex throughput

With a capacity for 4 slides, and average turnaround times of 30 minutes every 2 markers.

Your all-in-one, sample in data out hyperplex spatial biology solution.

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Product front view
  • Reagents Module

    Reagents and buffers are loaded in small and large volume reservoirs respectively and delivered to the sample through microfluidic channels.

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  • Microscope

    Compact fluorescent microscope. Images through the chip.

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  • Staining Module

    Rotary stage where up to four slides are inserted and clamped against the Imaging Chip. Its unique design allows for staining and imaging parallelization.

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  • Image Viewer

    Following image acquisition, the Viewer can open the resulting image files. The software facilitates visualization and exports the data for image analysis.

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Interested in acquiring a COMET™ solution for your lab?

Simplify your decision making process and technology adoption using your own samples and reagents.

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