COMET™
Rapid hyperplex made easy.
Your hyperplexing platform for spatial biology made easy
A full-stack solution capable of visualizing up to 40 markers in a single sample within a day.
An open solution without secrets
You are the owner of your research. Use your off-the-shelf, label-free antibodies and customize your protocols.
A high-throughput, high-insight platform
Get fast and deep insight into your samples’ spatial make-up with 4 slide capacity.
Using COMET™ means that we don’t need to conjugate or do anything to our primary antibodies, and for us this is important as we have a lot of in-house generated antibodies that we would like to apply.
DAPI Ki67 CD8 CD3 CD68 PARP A multiplexed image of colorectal core sample (human FFPE).
Lunaphore’s COMET™ is intuitive and flexible, we were able to work up a 30-plex IHC panel using our existing primary antibodies over a number of weeks. The data we generated provided us with a spatial, high-dimensional overview of immune infiltrate in COVID-19 placentitis and insight into the processes driving the pathology.
24-plex of human placenta in Sars-Cov-2 infected patient using COMET™
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24 markers on tonsil tissue.
Total protocol time: 5h. Fully automated on COMET™.
COMET™ helps by:
Allowing you to exploit the full capabilities of spatial biology in your research
- Gain a deep understanding of your tissue context and architecture.
- Leverage spatial knowledge to unveil potential new biomarkers.
- Gain true insight into immune microenvironments.
Leveraging the full potential of your discoveries
- Go from a discovery approach to zooming into your markers of interest all in one device.
- Integrate your RNA data with your proteomics data to gain true insight in biological processes.
Eliminating the complexity of spatial biology
- Move to a “sample in insight out” approach with minimal user investment.
- Get access to top-notch experts to support you in your research.
Join the COMET™
Revolution.
Fully automated workflow
COMET™ integrates the staining and imaging steps to avoid instrument manipulation during the entire process.
Use of your preferred antibodies
COMET™ is designed to satisfy researchers’ flexibility needs and works with off-the-shelf, label-free antibodies. As simple as that.
Hyperplex throughput
With a capacity for 4 slides, and average turnaround times of 30 minutes every 2 markers.
Your all-in-one, sample in data out hyperplex spatial biology solution.
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Reagents Module
Reagents and buffers are loaded in small and large volume reservoirs respectively and delivered to the sample through microfluidic channels.
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Staining Module
Rotary stage where up to four slides are inserted and clamped against the Imaging Chip. Its unique design allows for staining and imaging parallelization.
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Image Viewer
Following image acquisition, the Viewer can open the resulting image files. The software facilitates visualization and exports the data for image analysis.
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Interested in acquiring a COMET™ solution for your lab?
Simplify your decision making process and technology adoption using your own samples and reagents.