Spatial biology without compromises

Tissue morphology preservation and efficient antibody elution

Spatial immunofluorescence is a game-changer technique in the field of immuno-oncology, neuroscience, and infectious diseases. When developing multiplex immunofluorescence panels, tissue preservation and efficient antibody removal are key factors to ensure signal specificity. COMET™ is based on microfluidic technology and performs sequential immunofluorescence (seqIF™) with repetitive cycles of staining, imaging, and elution. COMET™ performs fast and finely controlled antibody staining incubations without harsh tissue photobleaching or tissue ablation.

Agenda:

  • How COMET™ guarantees efficient antibody elution while ensuring tissue morphology preservation;
  • How to assess epitope stability during seqIF™ assay;
  • How COMET™ enables marker stability up to 20 cycles across different tissue types and species.