SPYRE™ Amplification Kit
Make every marker count
While most protein markers can be detected with standard indirect immunofluorescence methods, markers with low signal levels sometimes remain difficult to visualize. The SPYRE™ Amplification, fully integrated with the COMET™ platform, amplifies the signal for low-expressed or hard-to-detect markers. It offers high-sensitivity detection you need without compromising on accuracy.
The SPYRE™ Amplification advantages

Sensitive
Enhanced detection of challenging or low-expressed markers tailored to COMET™.

Quantifiable
Detect faint signals while preserving quantification accuracy, ensuring reliable results.

Flexible
Amplify the signal of your target in any cycle of your seqIF™ panel using any off-the-shelf primary antibody of mouse or rabbit origin. The amplified signal can be eluted for consecutive rounds of detection.
Seamless integration with COMET™
Based on sequential immunofluorescence (seqIF™) technology, the sequential layered amplification (seqLA™) method enhances the detection of secondary antibodies bound to primary antibodies by utilizing linker molecules.