SPYRE™ Amplification Kit

Make every marker count

While most protein markers can be detected with standard indirect immunofluorescence methods, markers with low signal levels sometimes remain difficult to visualize. The SPYRE™ Amplification, fully integrated with the COMET™ platform, amplifies the signal for low-expressed or hard-to-detect markers. It offers high-sensitivity detection you need without compromising on accuracy.

The SPYRE™ Amplification advantages

Sensitive

Enhanced detection of challenging or low-expressed markers tailored to COMET™.

Quantifiable

Detect faint signals while preserving quantification accuracy, ensuring reliable results.

Flexible

Amplify the signal of your target in any cycle of your seqIF™ panel using any off-the-shelf primary antibody of mouse or rabbit origin. The amplified signal can be eluted for consecutive rounds of detection.

Seamless integration with COMET™

Based on sequential immunofluorescence (seqIF™) technology, the sequential layered amplification (seqLA™) method enhances the detection of secondary antibodies bound to primary antibodies by utilizing linker molecules.

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