Exploratory applications

At Lunaphore, we are innovators, striving to push the boundaries of research and scientific discoveries.

Lunaphore’s research team regularly works on exploratory projects and applications, with the aim of developing tools that can address a variety of new research questions.

Single-cell spatial multi-omics

An exploratory study was run to show fully automated co-detection of RNAs and proteins for up to 28 distinct targets on the same sample. This breakthrough study is the first to show the feasibility of workflow automation for single-cell multi-omic analysis. 

RNA and protein signals are stained and imaged on COMET™ without sample manipulation or any manual intervention, enabling standardization, scalability, and reproducibility.

COMET™’s microfluidic technology could drastically decrease turnaround times down to 30 minutes per RNA detection and 40 minutes per protein detection, preventing issues associated with RNA sample degradation.

How it works

Fully automated, from RNA to protein detection
Our microfluidic technology greatly decreases turnaround times
RNA and protein detection at single-cell level

Why spatial multi-omics

1. To identify secreted proteins correlating with RNA expression.

 

2. To detect additional targets such as splice variants mutations, highly homologous transcripts.

 

3. To identify active transcription factors and their target genes.

 

4. To identify low-expressed or difficult targets.

To learn more about spatial multi-omics, please download the whitepaper: