Lunaphore commercially launches HORIZON™ software to support COMET™ hyperplex image analysis

LAUSANNE, Switzerland – September 20, 2023 – 5:00 pm (CEST) – Lunaphore, a Swiss life sciences company developing technology to enable spatial biology in every laboratory, today announced the commercial product release of HORIZON™, an image analysis software designed for COMET™ hyperplex images. COMET™ is the only fully automated, high-throughput, hyperplex platform ensuring scalability and reproducibility without the need to conjugate primary antibodies, making panel design much more flexible and faster than any other hyperplex solution. HORIZON™ is part of the company’s product suite that provides the first universal, end-to-end spatial biology solution, answering the needs of the scientific community from early discovery to late-stage translational and clinical research.

HORIZON™ was developed by biologists for biologists to streamline the image analysis workflow. Tailored for COMET™ hyperplex images, HORIZON™ loads and navigates large datasets smoothly and allows side-by-side synchronous view of up to nine images. The intuitive interface with helpful visualization tools simplifies hyperplex image analysis and lowers the barrier for beginners. HORIZON™`s pre-trained, automatic nuclei segmentation algorithm provides accurate data for classification and downstream analysis within a few clicks.

“HORIZON™’s highlights are the nuclei segmentation tool and its ability to modulate the cell body expansion for a more accurate segmentation,” said Dr. Janusz Franco-Barraza, Assistant Research Professor at Fox Chase Cancer Center. “Also, the rule-based classification tool is not only fun to define cell populations, but also helps to visualize the logical cell classification process based on the presence or absence of distinctive markers using a decision tree-based format.”

With Lunaphore’s universal portfolio of precision automation solutions, including COMET™, SPYRE™ Antibody Panel kits, Secondary Antibodies, and HORIZON™, customers can leverage their existing antibody libraries and decades of know-how on Lunaphore’s platform to scale assays into endless multiplexing possibilities.

To learn more about the new products in Lunaphore’s universal, end-to-end solution or start placing requests, please get in touch with the team at: [email protected]

To learn more about Lunaphore, please visit: https://lunaphore.com/

About Lunaphore

Lunaphore Technologies S.A. is a Swiss company born in 2014 with the vision of enabling spatial biology in every laboratory. Lunaphore provides solutions based on a game-changing chip technology that can extract spatial proteomic and transcriptomic data from tumors and other tissues, transforming any assay into multiplex spatial biology through a streamlined and easily integrated process. Lunaphore empowers researchers in immunology, immuno-oncology, and neuroscience to push the boundaries of scientific discovery and drug development. Lunaphore’s technology enables the identification of biomarker “signatures” with clinical relevance to support the development of diagnostic tools and streamline clinical trials, to ultimately improve patient outcomes. For further information on Lunaphore and its products, please visit https://lunaphore.com.

About HORIZON™

HORIZON™ is a tissue analysis software designed to simplify image analysis and evaluation. Tailored to COMET™ hyperplex immunofluorescence images, HORIZON™ extends the COMET™ workflow, providing a seamless integration between both systems, from a hyperplex image to cell phenotyping. HORIZON™ leverages COMET™-generated images and associated protocol information instantaneously. It can support assay development on COMET™, as well as image analysis workflows, by rapidly obtaining precise single-cell data for custom downstream analysis. HORIZON™ can perform cell segmentation in a few clicks thanks to a COMET™-specific, pre-trained algorithm, and the user-friendly and intuitive interface enables hyperplex analysis with no coding experience. With HORIZON™, it is possible to take full control of hyperplex data, visualizing all image channels with full flexibility and accurately finetuning histograms to see the adjustments applied instantly. To learn more about the HORIZON™ software, please visit: https://lunaphore.com/products/horizon/

About COMET™

COMET™ is the only fully automated, high-throughput, hyperplex platform ensuring scalability and reproducibility without the need to conjugate primary antibodies. COMET™ provides walk-away automation, integrating staining, imaging, and image preprocessing steps to obtain standard hyperplex images. COMET™ generates highly robust and reproducible data with full tissue preservation, allowing researchers to perform downstream modalities such as H&E or transcriptomics using the same slide. Its superior tissue profiling capabilities facilitate the analysis of 40 different spatial markers in each automated run on a tissue slide. In contrast to other spatial biology solutions, COMET™ works with off-the-shelf, label-free primary antibodies, making panel design much more flexible and faster than any other hyperplex solution. COMET™ works with regular glass slides from standard histology workflows; it is validated for human and mouse samples and is compatible with any other animal sample. The platform can be used for a wide range of research applications, allowing for a dramatic improvement in the understanding of disease pathology. To learn more about the COMET™ platform, please visit: https://lunaphore.com/products/comet/

For further information contact:

Irene Tamayo

Lunaphore Corporate Communications

Email: [email protected]