Validation of Immunoscore for Prognostic Stratification in HPV-associated Oropharyngeal Cancer: An International Multicenter Study

New three-dimensional preclinical models to understand and treat liver cancers activated for the β-catenin pathway

Oncogenic and tumor-suppressive forces converge on a progenitor niche at the benign-to-malignant transition

Fibroblast-derived Collagen VI shapes the structure and function of the tumor-immune microenvironment in clear cell renal cell carcinoma

Binary-SPA: A Reference-Free Method for Cell Annotation in High-Resolution Spatial Transcriptomics

Minimal-invasive myocardial infarction model reproduces patient immune responses and reveals a pathogenic role for immature neutrophils

Longitudinal tumor ecosystem mapping defines glioblastoma treatment trajectories

Epithelial Plasticity and an Immune Suppressive Microenvironment Underpin Tumour Budding in Colorectal Cancer

Multimodal AI generates virtual population for tumor microenvironment modeling

Collagen remodeling promotes a GPCR-mediated mechanosensory immune checkpoint in ADGRG1+ CD8+ T cells and serves as a spatial biomarker of response to immunotherapy