Applications of In Situ Hybridisation and Spatial Profiling Methods in Research and Disease
May 16 - 17
Cancer Research UK Cambridge Institute
Join us in Cambridge for Applications of In Situ Hybridisation and Spatial Profiling Methods in Research and Disease.
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Form follows function and vice versa in biology. This principle underlies in situ analysis of DNA and RNA within intact cells, tissues, or whole organisms. Classic in situ nucleic acid hybridization techniques revolutionized the study of spatial dynamics in gene expression during organismal development, including sub-cellular RNA localization involved in specifying the developmental axis. In medicine, DNA in situ hybridization methods have been utilized in the diagnosis of hematological malignancies affecting patient management.
The field of in situ hybridization will continue to evolve and incorporate the latest advances from chemistry, microscopy, genomics, and computational analysis, perhaps making it even more challenging to implement. This symposium is a forum where practitioners of established or emerging in situ hybridization technologies come together to share unpublished know-hows and pitfalls with trainees, scientific peers, and industry partners.