October 27 - 28
San Francisco CA
Visit our booth #32
Discover true spatial multiomics
Discover spatial multiomics on COMET™️ by engaging directly with expert scientists. Experience firsthand how you can simultaneously detect RNA and protein markers within the same tissue section, all at a subcellular resolution.
Our protease-free, fully-automated workflow enables multiomics scalability for all stages of research. Are you interested in elevating your spatial biology projects with our multiomics solutions? Secure a meeting in one click to arrange a detailed discussion on how spatial multiomics can accelerate biomarker discovery and translation in biopharma.
October 27
Presentation
October 27
2:35 - 2:55 PM
Track 2: Identification, Qualification, & Validation Of Biomarkers In Translational Studies
There is an urgent need for more robust methods to differentiate immunotherapy responders from non-responders. Spatial biology, which examines cellular localization and interactions, is crucial for understanding the tumor-immune microenvironment. Here, we show how Lunaphore provides end-to-end solutions for spatial proteomics and spatial multiomics. We will present how the COMET™ platform performs sequential immunofluorescence (seqIF™) to obtain high-quality and reproducible data with standard off-the-shelf antibodies. We will explore our innovative multiomics application that combines RNAscope™ and seqIF™ to simultaneously identify RNA and protein targets on the same tissue section in a fully automated workflow. Additionally, we will present a novel multiplex imaging-based immunotherapy panel and a comprehensive analysis pipeline to characterize the spatial distribution and function of immune cells and their application for spatial biomarker detection in a cohort of immunotherapy-treated melanoma patients. Our distinctive spatial biology approach empowers scientists to identify new molecular signatures and bolster the development of targeted therapies.
Speaker
Rizwan Alam, Ph.D.
Field Application Specialist
Lunaphore