Spatial Biology beyond immuno-oncology - Flexibility to scale up discoveries

Charlotte Stadler is a co-director of the Spatial Biology Platform at Science for Life Laboratory. She is also the Head of the National Spatial Proteomics facility. She received her Ph.D. in 2012 within the framework of the Human Protein Atlas (HPA) project, with Prof. Emma Lundberg and Prof. Mathias Uhlén as her supervisors. During her PhD she established many of the protocols and pipelines for image based subcellular protein profiling that are used in the Human Protein Cell Atlas.
Today, her main focus is to develop and implement services and technologies that can be offered by the Spatial Proteomics Facility. Her internal research projects focus on the implementation of multiplexed imaging solutions into clinical practice but also on integrating different omics types for a more complete molecular understanding of the tissue sample biology. For more information: https://www.scilifelab.se/facilities/cell-profiling/ https://www.proteinatlas.org/

Jared K. Burks, Ph.D. is a prominent molecular biologist and technologist at MD Anderson Cancer Center, where he serves as a Professor and Associate Director of Shared Resources for the Cancer Center Support Grant (CCSG). Recognized by the National Cancer Institute (NCI) as a Research Specialist in Spatial Biology (R50 award), he specializes in spatial biology and has introduced several innovative technologies such as live cell imaging, eight-color TSA imaging, mass cytometry (suspension and imaging), and sequential immunofluorescence. Dr. Burks earned his Ph.D. in Biology from Texas A&M University, focusing on protein folding and trafficking under the National Academy member, Dr. Max D. Summers. He furthered his research at Baylor College of Medicine before joining MD Anderson, where he has directed a core facility for 14 years and founded the Innovation Nexus. The Innovation Nexus focusing on early adoption of novel technologies and has secured $5 million in novel technology partnerships within the last 18 months leading to multiple publications and funded grant awards. His current work involves developing methods for data integration to enhance understanding of cellular communications in tumors. He regularly serves as a Key Opinion Leader for various technology companies. Most recently he established the Lunaphore Comet sequential immunofluorescence system and introduced STOmics spatial transcriptomics. Through these technologies Dr Burks helped create a pipeline to combine spatial metabolomics, glycomics, pepidomics, proteomics, transcriptomics, and microbiome data in 3D to understand the functional interactions that occur in unique spatial niche. These efforts were driven to support a now funded U01 HTAN grant. Dr. Burks’ expertise in emerging technologies drives collaborative efforts that lead to significant advancements in cancer research and biology.

Charlotte Stadler is a co-director of the Spatial Biology Platform at Science for Life Laboratory. She is also the Head of the National Spatial Proteomics facility. She received her Ph.D. in 2012 within the framework of the Human Protein Atlas (HPA) project, with Prof. Emma Lundberg and Prof. Mathias Uhlén as her supervisors. During her PhD she established many of the protocols and pipelines for image based subcellular protein profiling that are used in the Human Protein Cell Atlas.
Today, her main focus is to develop and implement services and technologies that can be offered by the Spatial Proteomics Facility. Her internal research projects focus on the implementation of multiplexed imaging solutions into clinical practice but also on integrating different omics types for a more complete molecular understanding of the tissue sample biology. For more information: https://www.scilifelab.se/facilities/cell-profiling/ https://www.proteinatlas.org/