HORIZON™
A guided and intuitive tool for starting your COMET™ hyperplex image analysis.
Designed to simplify image analysis and evaluation
HORIZON™ is an image analysis software tailored to COMET™ hyperplex immunofluorescence images. The seamless integration between both systems lets you leverage the COMET™-generated images and associated protocol information instantaneously. Support your assay development on COMET™ as well as your image analysis workflow by rapidly obtaining precise single-cell data for your custom downstream analysis.
Get started with HORIZON™
Intuitive and guided interface
HORIZON™ provides a user‑friendly and guided environment that helps you navigate hyperplex image analysis with ease. Visualization tools, step‑wise workflows, and clear parameter controls provide support throughout your image analysis workflow.
Powerful analysis tools, no coding required
Access pre‑trained AI models, pre‑optimized parameters, and ready‑to‑use analytical tools for segmentation, phenotyping, neighborhood exploration, dimensionality reduction, and dot detection, all designed to help you generate high‑quality data quickly and confidently.
Seamless integration for COMET™ hyperplex images
Built specifically for COMET™ workflows, HORIZON™ loads, displays, and navigates large hyperplex datasets smoothly. You can perform marker‑ or nuclear-based segmentation, quantify protein and RNA expression at sub‑cellular resolution, and explore complex phenotypic patterns within your COMET™ images. Use the SPYRE(TM) Antibody Panel workflow template to rapidly apply pre-configured workflows for cell segmentation, phenotyping and spatial analysis across multiple samples and experiments.
Batch processing and shareable workflows
Scale your analysis across entire sample cohorts using batch image processing. Apply your workflows to multiple images or regions of interest and easily share them within your community to ensure consistency and collaboration across studies. Leverage standard GeoJSON file format for seamless import and export of cell segmentation annotations with third-party software.
The HORIZON™ workflow is designed for quick and reliable results

Facilitated transition from image to cell phenotyping using HORIZON’s guided or automated cell classification capabilities.
