EACR Webinar: "Mapping the tumor budding and its microenvironment in colorectal cancer using hyperplex immunofluorescence"

Title:
Mapping the tumor budding and its microenvironment in colorectal cancer using hyperplex immunofluorescence

Abstract:
Current colon cancer classification, prognostication, and therapy decisions are based mainly on cancer staging. However, additional biomarkers are needed to improve patient stratification and treatment decision-making strategies. Tumor budding (TB) is recognized as an independent prognostic factor in a variety of solid cancers. In this study we present the development of a multiplex immunofluorescence (mIF) panel for spatial characterization of TB and the tumor microenvironment.

Watch this webinar to discover how:

• mIF can be automated on the COMET™ platform using only non-conjugated primary antibodies
• mIF can streamline the extraction of valuable TB features in terms of marker expression
• TB phenotypes and their cellular neighborhood can help identify and better define their therapeutic potential for a personalized medicine approach.

Speakers:

• Dr. Cansaran Saygili Demir, University of Bern
• Bastian Nicolai, Lunaphore