Aging-Associated Decline in Macrophage STAT6-OXPHOS Programs Promotes Tumor-Like Multinucleated Syncytia

Integrated Spatial Multi-omic Profiling Identifies HSV-associated Inflammatory Macrophage Niches Linked to Oncolytic Virotherapy Response in Melanoma

Niche-level immune evasion in TP53 mutant AML residual disease revealed by spatial proteomics

Targeting the epithelium in pulmonary fibrosis

Spatially resolved ex vivo drug response profiling in SMARCB1-deficient sinonasal carcinoma

Integrated multi-omics identifies distinct macrophage alterations during progression of metabolic dysfunction-associated steatohepatitis

The abscopal effect of IRE combined with anti–PD-1 achieves local ablation and systemic control of PDAC

Glucose selectively drives a rapid oxidative burst and immunometabolic reprogramming in human neutrophils during Mycobacterium tuberculosis infection

IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma

Integration of spatial single-cell proteomics and spatial metabolomics reveals tumor microenvironment predictive of immunotherapy response in mucosal melanoma