Matched pancreatic cancer liver metastatic model system reveals cancer cell-dependent organotropism and site-specific tumor microenvironment reflective of human disease

CSF1R-dependent CD169-positive macrophages locally constrain melanoma growth in the skin

IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma

Integration of spatial single-cell proteomics and spatial metabolomics reveals tumor microenvironment predictive of immunotherapy response in mucosal melanoma

Spatial predictors of response to chemo-immunotherapy in microsatellite stable metastatic colorectal cancer

Rewiring Oncogenic Transcriptional Complexes with Domain- ALTeration Chimeras (DALTACs) in Prostate Cancer

Single-nucleus profiling reveals hepatocyte identity and immune features associated with corticosteroid response in severe alcohol-related hepatitis

Tumour cell-intrinsic complement C1r and C1s regulate cancer cell fitness and shape the immune microenvironment in triple-negative breast cancer

Validation of Immunoscore for Prognostic Stratification in HPV-associated Oropharyngeal Cancer: An International Multicenter Study

New three-dimensional preclinical models to understand and treat liver cancers activated for the β-catenin pathway